Research reveals blood type plays major role in liver disease risk
New Delhi (The Uttam Hindu): We often associate our blood type only with blood donations or transfusions, but a new study suggests it may also be linked to our liver health. Researchers believe blood type may indicate a person's risk of developing serious liver disease in the future.
A study found that people with certain blood types have a higher risk of liver disease, while others have a lower risk. According to the study, those with blood type B had a slightly lower risk of serious liver disease, while those with other blood types had a higher risk.
At the same time, research has also revealed that individuals with blood type A have a higher risk of autoimmune liver disease. In this condition, the body's immune system attacks the liver itself, causing gradual liver damage and, in severe cases, even liver failure.
In autoimmune liver disease, the immune system mistakenly attacks the liver, causing inflammation and damage to liver cells. If left untreated, this long-term disease can lead to liver cirrhosis, liver cancer, or liver failure.
For many years, scientists have been trying to understand how blood type affects the risk of various diseases. Previous research suggests that people with non-O blood types (A, B, AB) have higher levels of certain blood clotting factors, which may have a mild effect on blood flow to the liver.
These groups also have higher levels of a protein called von Willebrand factor, especially in those with pre-existing liver disease. While this isn't considered a major risk factor, it may be a small contributing factor.
Which blood types are associated with autoimmune liver diseases?
Autoimmune hepatitis (AIH): This is where the immune system attacks liver cells.
Primary biliary cholangitis (PBC): This is where the bile ducts inside the liver gradually become damaged.
The study found:
The risk of autoimmune hepatitis is higher in those with blood type A.
The risk of primary biliary cholangitis is lower in those with blood type B.
Routine checkups are important.
If you have blood type A or B and a family history of liver disease, regular liver function tests and periodic checkups with a doctor can be beneficial. This can help detect potential liver problems early and allow for timely treatment.